Now showing items 1-10 of 10

    • Araya, Eyleen; Olmedo, Ivonne; Bastus, Neus G.; Guerrero, Simón; Puntes, Víctor F.; Giralt, Ernest; Kogan Bocian, Marcelo (SPRINGER, 2008-11)
      Peptide-Gold nanoparticles selectively attached to beta-amyloid protein (A beta) amyloidogenic aggregates were irradiated with microwave. This treatment produces dramatic effects on the A beta aggregates, inhibiting both ...
    • Olmedo, Ivonne; Araya, Eyleen; Sanz, Fausto; Medina, Elias; Arbiol, Jordi; Toledo, Pedro; Álvarez Lueje, Alejandro; Giralt, Ernest; Kogan Bocian, Marcelo (American Chemical Society, 2008-05-30)
      In a previous work, we studied the interaction of -amyloid fibrils (A ) with gold nanoparticles (AuNP) conjugated with the peptide CLPFFD-NH2. Here, we studied the effect of changing the residue sequence of the ...
    • Olmedo Alegría, Ivonne Odette; Araya, Eyleen; Sanz, F.; Medina Consuegra, Elías Daniel; Arbiol, Jordi; Toledo, P.; Álvarez Lueje, Alejandro; Giralt, Ernest; Kogan Bocian, Marcelo (AMER CHEMICAL SOC, 2008-06)
      In a previous work, we studied the interaction of P-amyloid fibrils (A beta) with gold nanoparticles (AuNP) conjugated with the peptide CLPFFD-NH2. Here, we studied the effect of changing the residue sequence of the peptide ...
    • Kogan Bocian, Marcelo; Bastus, Neus G.; Amigo, Roger; Grillo-Bosch, Dolors; Araya, Eyleen; Turiel, Antonio; Labarta, Amilcar; Giralt, Ernest; Puntes, Víctor F. (AMER CHEMICAL SOC, 2006-01)
      The local heat delivered by metallic nanoparticles selectively attached to their target can be used as a molecular surgery to safely remove toxic and clogging aggregates. We apply this principle to protein aggregates, in ...
    • Bolaños, Karen; Sánchez Navarro, Macarena; Tapia Arellano, Andreas; Giralt, Ernest; Kogan, Marcelo Javier; Araya, Eyleen (MDPI, 2021)
      Gold nanoparticles (AuNPs) have been shown to be outstanding tools for drug delivery and biomedical applications, mainly owing to their colloidal stability, surface chemistry, and photothermal properties. The biocompatibility ...
    • Salas Huenuleo, Edison Sebastián; Hernández Jorquera, Andrea Carolina; Lobos González, Lorena; Polakovicová, Iva; Morales Zavala, Francisco Andrés; Araya, Eyleen; Celis, Freddy; Romero Osses, Carmen Aurora; Kogan, Marcelo Javier (MDPI, 2022)
      One of the recent attractive therapeutic approaches for cancer treatment is restoring downregulated microRNAs. They play an essential muti-regulatory role in cellular processes such as proliferation, differentiation, ...
    • Velasco Aguirre, Carolina; Morales, Francisco; Gallardo Toledo, Eduardo; Guerrero, Simón; Giralt, Ernest; Araya, Eyleen; Kogan Bocian, Marcelo (Dove Medical Press, 2015)
      An exciting and emerging field in nanomedicine involves the use of gold nanoparticles (AuNPs) in the preclinical development of new strategies for the treatment and diagnosis of brain-related diseases such as neurodegeneration ...
    • Richter Duk, Pablo; Toral Ponce, María; Parra Ortíz, María Valentina; Fuentes, Sandra; Araya, Eyleen (Sociedad Chilena de Química, 1995)
      Se desarrolla un método automático de análisis por inyección en flujo (FIA) para la determinación simultánea de hierro y titanio en mezclas. El método se basa en el diseño de una configuración FIA que incluye la reducción ...
    • Araya, Eyleen; Kogan Bocian, Marcelo; Guell, Aleix G.; Escobar, Carlos A.; Sanz, Fausto (2014)
      A hydrogen-terminated Si (111) surface was modified to form an aminoterminated monolayer for immobilization of streptavidin. Cleavage of an N-(ω- undecylenyl)-phthalimide covered surface using hidrazine yields an amino ...
    • Báez, Daniela F.; Gallardo Toledo, Eduardo Ignacio; Oyarzun, María Paz; Araya, Eyleen; Kogan, Marcelo Javier (Dovepress, 2021)
      The physicochemical and optical properties of silver nanoparticles (SNPs) and gold nanoparticles (GNPs) have allowed them to be employed for various biomedical applications, including delivery, therapy, imaging, and as ...